A proven, integrated solution for life science companies contemplating traditional or alternative paths to the US capital markets
We are the life science industry’s go-to resource for comprehensive IPO preparation and execution services – with 50 transactions successfully completed since 2013 and dozens of additional filings.
We bring deep sector-specific knowledge and relationships to the IPO process and understand the timelines, requirements and challenges that are unique to this space. Our services range from strategic leadership to operational finance support and technical accounting, available in part or whole at any stage of the process and beyond.

Meet one of our experts
Gregg Beloff, Co-founder and Managing Director
Key Considerations
- One path does not suit all. We are experienced in both traditional and non-traditional routes to the US capital markets, including SPAC transactions and reverse mergers, as well as cross-border IPO transactions for prospective registrants in Europe and beyond.
- Seamless execution requires coordination among numerous players. We have extensive relationships with Big 4 auditors, SEC counsel and life science investment bankers, allowing for close collaboration throughout the entire IPO process.
- Expertly managed preparation, beginning at least six months in advance, is the difference maker in being able to jump when the window of opportunity opens.
How Danforth Can Help
Process Management
An IPO is a unique, intense and critically important journey. We help you navigate this process by being a thought partner, technical partner and supplemental support service network.
Buy and Sell Side Support
We manage the investment banking syndicate, support TTW communications and prepare the roadshow – whether conducted virtually or in person.
Financial Planning & Analysis
We prepare budgets, long-range plans and cost analyses which can support corporate planning, buy and sell side discussions and SEC disclosure.
Risk Mitigation
We mitigate accounting and reporting risk, providing project management, expert technical advice and frictionless execution to accomplish a successful and timely offering. We can also activate our risk management specialists to ensure accurate reporting of potential risk factors in your Form S-1 and other documentation. Click here for information about our risk and insurance management services.
Public Readiness
We advise on corporate governance, risk management, insurance, policies and procedures and Sarbanes-Oxley compliance.
Audit Preparation
We prepare for external PCAOB audits and SEC-compliant financial reporting, including disclosure “upgrades” for EPS calculations, pro-forma presentations, segmental reporting, going concern disclosures, related-party matters and taxation disclosures. Our Accounting and Reporting Advisory team routinely manages this work and other technical aspects of IPO preparation.
Form S-1 Financials
We lead or supplement your team in the preparation of historical financials, selected and pro-forma financial data, and other financial elements of your S-1 registration statement/prospectus in compliance with SEC requirements.
Form S-1 Business Section
We have drafting specialists who draw upon their backgrounds in life science investment banking and public and private equity financings to position your company in a compelling way for investors.
Strategic Communications
Argot Partners, a Danforth company, brings a depth of knowledge and discipline to the process of offering your securities to the public for the first time, and can work in close coordination with Danforth CFOs to manage strategic communications and investor relations. Learn more here.
How else can we help?
Learn about our additional capabilities